Classical Age
In the fifth and fourth centuries BCE, Kos became the seat of one of the most famous medical traditions of antiquity, centered on Hippocrates, 'the father of medicine.' The Coan school taught that disease arises from natural causes rather than divine punishment, observed patients closely, and gave its name to the vast Hippocratic Corpus and the physician's oath. The island lay within the world of the Athenian alliance and the contests of the Greek city-states before falling, like the rest of the Aegean, under Macedonian sway.